Best Practices for Cataloging Objects Using RDA and MARC 21

This best practices document is intended to assist catalogers in creating bibliographic records for objects, which RDA refers to as three dimensional forms, according to RDA instructions. This document provides guidance for the most common object situations encountered in libraries. Each section includes examples that reflect the RDA instructions. A list of resources and a selection of full MARC record examples illustrating common situations encountered in cataloging objects (of various types) completes the document. The Objects Task Force especially worked on the examples to provide a variety of materials that fall bibliographically under Objects. The Task Force found at least one example of Realia, Toy, Model, Art Original, Game, Microscope Slide, Diorama, and Tactile Three-Dimensional Form. This document is intended for use with Resource Description and Access (RDA) and the MARC21 Format for Bibliographic Data. This document does not replace the use of RDA, but it works in tandem with RDA to provide best practices guidance in cataloging objects. This document is also not a step-by-step guide on how to catalog objects. The best practice recommendations and cataloging examples presented in the document are intended to clarify RDA principles and instructions used in cataloging objects. These guidelines assume some familiarity with RDA. Subject analysis is not fully covered in this best practices guide. Classification is not covered. Name and topical subject access points, as well as genre/form information, are not covered fully in this document, although we do provide a section to discuss access points on a very practical level, and certainly, they do appear in the MARC record examples

OLAC Best Practices for Cataloging DVD-Video and Blu-ray Discs, Objects, Streaming Media, and Video Games Using the Original RDA Toolkit and MARC 21

The OLAC Unified Best Practices Guide brings together the current published best practice guides into a single best practices guide that incorporates Best Practices for Cataloging DVD-Video and Blu-ray Discs Using RDA and MARC21, Best Practices for Cataloging Objects Using RDA and MARC 21, Best Practices for Cataloging Streaming Media Using RDA and MARC21, and Best Practices for Cataloging Video Games Using RDA and MARC21

Full MARC Examples to Accompany OLAC Best Practices for Cataloging DVD-Video and Blu- ray Discs, Objects, Streaming Media, and Video Games Using the Original RDA Toolkit and MARC 21

Examples of MARC 21 catalog records to accompany the OLAC Best Practices for Cataloging DVD-Video and Blu-ray Discs, Objects, Streaming Media, and Video Games Using the Original RDA Toolkit and MARC 21

Best Practices for Cataloging Video Games Using RDA and MARC21

While a cataloger with experience handling different formats will find that many concepts extend to video games, there are a few ‘quirks’ to the format that those unfamiliar with video games should know about

Volume 43, Number 3, September 2023 OLAC Newsletter

Digitized September 2023 issue of the OLAC Newsletter

Best Practices for Cataloging DVD-Video and Blu-ray Discs Using RDA and MARC21

Best Practices for Cataloging DVD-video and Blu-ray Discs Using RDA and MARC21 builds upon the work of the 2008 Guide to Cataloging DVD and Blu-ray Discs Using AACR2r and MARC21, which in turn updated the 2002 Guide to Cataloging DVDs Using AACR2r Chapters 7 and 9 created by the DVD Cataloging Task Force of OLAC. The focus of this new document is to provide a set of “best practice” recommendations rather than a step-by-step instruction manual for cataloging DVD-video and Blu-ray Discs. One reason for this shift is that RDA cataloging practice is far from settled, particularly in regard to special format materials. Best practice recommendations will likely be easier to manage as RDA instructions evolve. This document is intended for use with Resource Description and Access (RDA) and the MARC21 Format for Bibliographic Data. It should not be considered a substitute for the RDA Toolkit. The best practice recommendations and cataloging examples presented in the document are intended only to clarify RDA principles and instructions used in cataloging DVD-video and Blu- ray Disc formats

Developing an Australian Melanoma Clinical Outcomes Registry (MelCOR): a protocol paper

Introduction Australia has the highest incidence of melanoma in the world with variable care provided by a diverse range of clinicians. Clinical quality registries aim to identify these variations in care and provide anonymised, benchmarked feedback to clinicians and institutions to improve patient outcomes. The Australian Melanoma Clinical Outcomes Registry (MelCOR) aims to collect population-wide, clinical-level data for the early management of cutaneous melanoma and provide anonymised feedback to healthcare providers. Methods and analysis A modified Delphi process will be undertaken to identify key clinical quality indicators for inclusion in the MelCOR pilot. MelCOR will prospectively collect data relevant to these quality indicators, initially for all people over the age of 18 years living in Victoria and Queensland with a melanoma diagnosis confirmed by histopathology, via a two-stage recruitment and consent process. In stage 1, existing State-based cancer registries contact the treating clinician and provide an opportunity for them to opt themselves or their patients out of direct contact with MelCOR. After stage 1, re-identifiable clinical data are provided to the MelCOR under a waiver of consent. In stage 2, the State-based cancer registry will approach the patient directly and invite them to opt in to MelCOR and share identifiable data. If a patient elects to opt in, MelCOR will be able to contact patients directly to collect patient-reported outcome measures. Aggregated data will be used to provide benchmarked, comparative feedback to participating institutions/clinicians. Ethics and dissemination Following the successful collection of pilot data, the feasibility of an Australia-wide roll out will be evaluated. Key quality indicator data will be the core of the MelCOR dataset, with additional data points added later. Annual reports will be issued, first to the relevant stakeholders followed by the public. MelCOR is approved by the Alfred Ethics Committee (58280/127/20)

Best Practices for Cataloging DVD-Video and Blu-ray Discs Using RDA and MARC21 Version 1.1

Purpose Best Practices for Cataloging DVD-video and Blu-ray Discs Using RDA and MARC21 builds upon the work of the 2008 Guide to Cataloging DVD and Blu-ray Discs Using AACR2r and MARC21, which in turn updated the 2002 Guide to Cataloging DVDs Using AACR2r Chapters 7 and 9 created by the DVD Cataloging Task Force of OLAC. The focus of this new document is to provide a set of “best practice” recommendations rather than a step-by-step instruction manual for cataloging DVD-video and Blu-ray Discs. One reason for this shift is that RDA cataloging practice is far from settled, particularly in regard to special format materials. Best practice recommendations will likely be easier to manage as RDA instructions evolve. This document is intended for use with Resource Description and Access (RDA) and the MARC21 Format for Bibliographic Data. It should not be considered a substitute for the RDA Toolkit. The best practice recommendations and cataloging examples presented in the document are intended only to clarify RDA principles and instructions used in cataloging DVD-video and Blu- ray Disc formats. The opening section provides a general overview of DVD and Blu-ray technology, disc characteristics, plus a comparison with compact disc (CD) technology. A brief introduction to RDA follows, to provide a basic frame of reference for the document. Since most libraries are still encoding data in MARC21, the main part of the document is generally arranged by RDA element in the order they are encountered in a MARC21 record. Each section includes examples that reflect the principles outlined in the document. Examples use ISBD as the presentation format. A table outlining recommended description and encoding of DVD-Video and Blu-ray Disc attributes is given in the appendix. A list of resources and a selection of full MARC21 record examples illustrating common situations encountered in DVD-Video and Blu-ray Disc cataloging completes the document

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two

Background The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd. Methods We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background. Results First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001). Conclusions In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival